|Product Name||Specification||Sweetness(Compare with sugar)|
|Stevia Rebaudioside A (Free of Bitterness)||97%-98%||300 times|
|HERBAL PROPERTIES AND ACTIONS|
|Main Actions||Other Actions||Standard Dosage|
|naturally sweeten||kill bacteria||Leaves|
|lower blood sugar||kill fungi||Ground leaves: 1/4 tsp|
|increase urination||kill viruses||1 tsp of sugar|
|lower blood pressure||reduce inflammation||Infusion: 1 cup 2-3|
|dilate blood vessels||times daily|
Stevioside is extracted from compositae plant stevia leaves, it is natural, high sweet, low quantity of heat and safety sweetener. After eating, it does not participate in the metabolism in the human body, and as prototype form excreted from the stool. Therefore, to some patients with specific diseases, stevia can regulate blood glucose and lipid, blood pressure, stimulate insulin secretion. It can possess anti-neoplastic properties, have anti-bacterial and anti-inflammatory effect, and protect liver and stomach. Stevia is known as “plant sugar king”, “best natural sweetener”, “the most promising future of sweetener” by the world health organization.
Stevioside is white, yellowish powder or crystal. Its sweetness of sucrose is 200 ~ 450 times, while the heat only sugar 1/300.
A number of studies have suggested that, beside sweetness, stevioside along with related compounds, which include rebaudioside A (second most abundant component of S. rebaudiana leaf), steviol and isosteviol (metabolic components of stevioside) may also offer therapeutic benefits, as they have anti-hyperglycemic, anti-hypertensive, anti-inflammatory, anti-tumor, anti-diarrheal, diuretic, and immunomodulatory actions.
Stevioside is widely used in food, beverage, pharmaceutical, cosmetics, spices, pickles and other fields.
The possible anti-hyperglycemic actions of stevioside and related compounds
Stevioside inhibits glucose production (minus sign) by
1) inhibiting glucagon secretion from α cell of pancreas which affects both gluconeogenesis and glycogenolysis.
2) direct suppression of phosphoenol pyruvate carboxy kinase (PEPCK) activity, a rate limiting enzyme in gluconeogenesis in the liver.
All of which causes a reduction of glucose release from the liver.
On the other hand, stevioside, steviol and rebaudioside A stimulate glucose uptake (plus sign) by increasing insulin secretion from β cell of pancreas and enhancing insulin sensitivity of peripheral tissues promoting glucose uptake. Therefore, they exhibit antihyperglycemic action by reducing glucose production while increasing glucose uptake to maintain plasma glucose balance.